23 February 2010

Sam Sisodia on the Brain
Tuesday, February 23, 5:30-8:30pm
19 South Wabash, 2d floor

Cocktails at 5:30, presentation 6:00-6:30 followed by discussion and more cocktails. 
 $40 includes drinks, two cigars, and sandwiches. 
Reservations are required.

Sam Sisodia, Thomas Reynolds Sr. Family Professor of Neurosciences and Director of the Center for Molecular Neurobiology at the University of Chicago, will talk about his research on the causes of Alzheimer's Disease.

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the deposition of A-beta peptides in senile plaques in the brains of affected individuals. Familial Alzheimer’s disease (FAD) is caused by inheritance of genes encoding mutant variants of amyloid precursor proteins (APP) or presenilin (PS). My lecture will focus on the role of these mutant proteins in the generation of neurotoxic A-beta-species that impair synaptic function. In parallel, I will emphasize insights that have emerged from studies of transgenic mice that exhibit A-beta deposits and the impact of environmental enrichment and exercise in modulating A-beta deposition and the generation of new neurons in the brains of these animals.  Finally, I will describe the status of therapeutic modalities and clinical trials aimed at attenuating A-beta deposition.

Dr. Sangram Sisodia has received several awards, including the  Potamkin Prize for Alzheimer's Disease Research from the American Academy of Neurology (1997); the Metropolitan Life Foundation Award for Medical Research (1998); Presidential Special Lecturer at the Annual Society for Neuroscience Meeting in 2001 and 2006; and membership in the Johns Hopkins Society of Scholars (2007) and Fellow of the American Association for the Advancement of Science (AAAS) (2009).  Dr. Sisodia has served on the scientific review and advisory committees of the federal and non-federal agencies, including: NLS1 (NIH) Study Section ('95-'97); Member, NIA Board of Scientific Counselors ('99-''04); SFN Program Committee (2007-).  He serves on the Editorial Boards of eight journals, including Neuron and Cell and is a member of the Dana Alliance for Brain Initiatives and Faculty of 1000 Biology.


He received his B.A. from the College of Wooster in Ohio and his Ph.D. in Biochemistry from the University of Georgia. He joined The Johns Hopkins University School of Medicine as a Postdoctoral Fellow in 1985, where he rose to the rank of Professor of Pathology and Neuroscience.  He then moved to The University of Chicago in 1998 to assume the Chairmanship in the Department of Neurobiology, Pharmacology and Physiology. 

Coming up

Tuesday, March 16
Asad Hayaud Din, Consul of Pakistan, will take questions about Pakistan, Afghanistan, India, and the world.

Tuesday, March 30
Emanuel Mayer, Ass't Professor of Classics at the University of Chicago, will talk about kitsch in ancient Roman art, the rise of the middle class, and the history of the garden gnome.

Tuesday, April 13
Lee Allison, President of the Lee Allison Company, will talk about style.

Tuesday, April 27
Bill Daley, food and wine critic for the Chicago Tribune, will lead a wine and cigar tasting.

About the Cigar Society of Chicago

ONE OF THE OLDEST AND greatest traditions of the city clubs of Chicago is the discussion of intellectual, social, legal, artistic, historical, scientific, musical, theatrical, and philosophical issues in the company of educated, bright, and appropriately provocative individuals, all under the beneficent influence of substantial amounts of tobacco and spirits.  The Cigar Society of Chicago embraces this tradition and extends it with its Informal Smokers, University Series lectures, and Cigar Society Dinners, in which cigars, and from time to time pipes and cigarettes, appear as an important component of our version of the classical symposium.  To be included in the Cigar Society's mailing list, write to the Secretary at CigarSociety@logicophilosophicus.org.